So did I, Julian. Jo Lis, had brought it up in a comment, too. So here is what I responded:
His arguments, presented eloquently as usual, are wrong on several levels. I could (and possibly will) write an entire article about how his post illustrates misinterpretation of data and studies, (intentional or accidental).
That post will take some time to write, which is why I’m “cherry-picking” just one of his arguments, because it illustrates his misinterpretation quite clearly.
I quote
“Further, platelet-rich plasma is not representative of the concentration of platelets normally found in human blood, so not only did the investigators need to use unusually high concentrations of xylitol to see an effect on platelet aggregation, but they also needed unusually high concentrations of platelets.”
Unquote
He ignores two facts here: First, the researchers demonstrated the aggregation response not only in platelet rich plasma (PRP) but also in whole blood.
I quote from the study:
“Since our studies with isolated washed human platelets, PRP, whole blood, and murine in vivo thrombosis models all suggested that xylitol can impact platelet responsiveness…”
Second, many studies have counterintuitively shown that platelet aggregation response is actually reduced in PRP compared to whole blood. That contradicts and invalidates his argument. He presents several similarly unsupported arguments in his post.
Now, that you are the second reader to bring it up, I'll definitely write this post.