If your objective is to increase NO availability for the working muscle, then arginine supplementation may not be the best ption. Orally supplemented arginine has a very low bioavailability, and may even harm the liver, depending on the amount of intake. But you can circumvent this issue by supplementing with citrulline instead of arginine. The reason is the arginine-citrulline-NO cycle. Nitric oxide synthase is the enzyme that produces NO from arginine precursor. One fallout product of this reaction is citrulline (another amino acid). But citrulline is recycled back into arginine two enzymes that convert it back to arginine. Now you can imagine that adding citrulline to this cycle will indirectly increase arginine. The beauty about this is that citrulline supplementation has no side effects and orally taken citrulline has a high bioavailability. That’s the major reason why I take citrulline daily as a supplement. I’m not sure about the effect on muscle soreness. I personally don’t avoid it, because it gives me feedback whether my training was sufficiently “heavy” to stimulate an adaptive response. You need to experiment with this. I’m keen to hear about your experience if you choose to do the experiment.